Journal of Complexity in Health Sciences: Table of Contents

Emotional intelligence developing training program’s impact on teachers’ psycho-emotional state

Joffe-Luiniene, Roza — 2021-12-29T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 4, Issue 2, 2021, p. 45-54.
Roza Joffe-Luiniene, Artiomas Sabajevas, Evelina Vainoriene, Violeta Gaveliene, Aleksandr Miskelovic, Ruta Milisauskiene, Julita Piguleviciene, Alfonsas Vainoras
Teachers’ profession is widely described as a mentally challenging one, often leading to burnout. As emotional exhaustion is higher among representatives of this occupation in comparison to other highly emotionally challenging professions, it is important to help teachers gain necessary skills and tools in order to maintain good emotional and overall wellbeing, and effectively cope with daily stressors. The aim of the study described in this paper was to assess the impact of a 5-module emotional intelligence developing training program on teachers’ psycho-emotional health. Study sample consisted of 45 teachers, who took part in the study, filling in the research questionnaires before and after the completion of the designed training program. Participants were asked to subjectively rate their level of stress and other parameters, defining their subjective wellbeing. Results of the study revealed that after completing the training program, participants indicated a statistically significantly lower level of stress (p< 0.01). Also, participants’ subjective evaluation of the quality of their social relationships and their overall wellbeing was significantly higher (p< 0.01) after the training program completion.

“The tonic’s not always in a bottle”: a qualitative study investigating a heart rate variability biofeedback coherence intervention for individuals with gastrointestinal disorders

Field, Lucy — 2022-06-30T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 5, Issue 1, 2022, p. 1-14.
Lucy Field, Mark Forshaw, Helen Poole, Peter Paine, Gillian Fairclough, Candice Walton
Gastrointestinal disorders (GID) affect psychological and physical health and can be impacted by stress and ability to self-regulate emotions. The aim of this study was to gain an in-depth understanding of individuals with GID experiences of a Heart Rate Variability biofeedback (HRV-BF) coherence intervention. Six patients, who had already been diagnosed with GID, were interviewed using a semi-structured interview schedule to investigate how engaging in an HRV-BF coherence intervention affected their levels of stress and their GID condition. All transcripts were explored using Interpretative Phenomenological Analysis (IPA). Analysis of the accounts indicated four superordinate themes: (1) Autonomy, (2) Self-regulation, (3) Acceptance, (4) Mind-Body-Spirit. The field of HRV-BF interventions in the area of gastroenterology is promising. However, it is recommended that further studies involving psycho-physiological interventions, with mixed-method designs and larger samples, are undertaken.

Correlation between ST-elevation myocardial infarction, non-ST-elevation myocardial infarction and the local Earth’s magnetic field changes

Vanagaitė, Giedrė — 2022-06-30T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 5, Issue 1, 2022, p. 15-21.
Giedrė Vanagaitė, Gabrielė Jakuškaitė, Greta Žiubrytė, Mantas Landauskas, Alfonsas Vainoras, Rollin McCraty, Gediminas Jaruševičius
Stronger oscillations in the local Earth magnetic field may have an impact on the course of ischemic heart disease. This effect is individual for every person and depends on the sex, age, living territory, season, capability to adjust to magnetic field fluctuations and health status. Individuals who already have cardiovascular disease are more sensitive to magnetic field fluctuations, therefore further research is needed to make conclusions. Aim: To identify correlations between changes in local Earth magnetic field frequencies and patients with ST segment elevation myocardial infarction (STEMI) and non-ST segment elevation myocardial infarction (NSTEMI) cases per week, cases by sex per week and patients’ blood laboratory parameters (low-density lipoprotein cholesterol and Troponin I level). Methods: A retrospective study of 1667 patients, who were admitted to the Hospital of Lithuanian University of Health Sciences Kaunas Clinics between 1st January and 31st December 2019 due to acute coronary syndrome (STEMI and NSTEMI), were included in the study. Local Earth's time varying magnetic field (TVMF) was measured by a magnetometer located in Baisogala, Lithuania. Data from the magnetometer was collected daily, and weekly averaged. We assessed the correlations between average weekly geomagnetic field strength in six different frequency ranges (Hz) and average number of STEMI and NSTEMI cases per week, cases by sex per week and patients’ blood laboratory parameters (low-density lipoprotein cholesterol and Troponin I level). Results: The presence of a stronger magnetic field in the frequency range of 32-65 Hz was significantly related to the number of cases in the STEMI group during the winter season (r= 0.583, p= 0.036). Tendency towards a positive correlation was found during the winter in the men's group with STEMI in the high frequency range of 32-65 Hz. Low-density lipoprotein cholesterol level correlated positively in the winter STEMI group with the magnetic field in the 32-65 Hz range, and in the autumn STEMI group with the magnetic field in the frequency range of 0-7 Hz. Conclusion: Increased geomagnetic field strength in the high frequency range of 32-65 Hz is associated with a higher number of cases in the STEMI group.

Modern biophysical view of electromagnetic processes of the phenomenon of life of living biological systems as a promising basis for the development of complex medicine: the role of cell membranes

Nevoit, Ganna — 2022-06-30T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 5, Issue 1, 2022, p. 22-34.
Ganna Nevoit, Inga Arune Bumblyte, Maksim Potyazhenko, Ozar Minser
The results of a theoretical study of the role of cell membranes in electromagnetic generation and in the process of realizing the phenomenon of life are presented in the article. The aim of the theoretical study was to summarize the existing scientific physical and biological knowledge of modern science about the electromagnetic processes of the phenomenon of life at the cellular level in order to deepen the fundamental knowledge of complex medicine. This study is a fragment of research work on “The development of algorithms and technologies for implementing a Healthy Lifestyle in patients with Noncommunicable Diseases based on the study of functional status” (state registration number 0121U108237: UDC 613 616-056-06: 616.1/9-03). General scientific methods and theoretical methods were used in this theoretical study. The main conclusions of the theoretical study were made as follows: 1) Cell membranes can be considered one of the main morphological structures of electromagnetic generation at the cellular level. 2) Cell viability is ensured by electromagnetic generation and electromagnetic generation of cells can be considered as a separate important function of membranes in addition to those already defined, as it provides signaling. 3) The end result of electromagnetic generation of cell membranes and all molecules of the cell is its own electromagnetic fields, which have a millimeter wavelength range with a frequency of 1010-1011 Hz and they are a quantum mechanical result of electromagnetic generations, perform the information-energy function in intercellular interaction in vivo.

Early physiotherapy and chest wall oscillation in patients with COVID-19 disease at the intensive care unit: a pilot clinical trial

Rutkauskienė, Laura — 2022-12-04T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 5, Issue 2, 2022, p. 35-44.
Laura Rutkauskienė, Goda Strautnikaitė, Deividas Rutkauskas, Tomas Tamošuitis, Raimondas Kubilius, Inesa Rimdeikienė
Over the past few years, the early mobilization and rehabilitation of patients in the intensive care unit (ICU) has drawn a lot of interest from the clinical and scientific communities. An interdisciplinary team treating patients suffering from serious conditions should include physiotherapy. Additionally, physiotherapy is utilized to treat and prevent the side effects of extended immobility or sleep, as well as to improve respiratory function. The purpose is to improve residual functionality; to avoid new and repeated hospitalizations; to improve health and quality of life. Exercises for the entire body (including early in-bed cycling), specialized breathing exercises, chest mobilization, relief help, drainage postures, vibration, verticalization, and passive movements are all crucial components of COVID-19 physiotherapy. Our goal was to evaluate the changes of functional condition of patients with COVID-19 in the acute stage using different physiotherapy methods: complex measures against mono therapy. In the research, 28 subjects (15 men and 13 women) were involved. A total of 84 physiotherapy procedures were performed. In the first group, breathing exercises and chest wall oscillation were applied, in the second group – only chest wall oscillation. Respiratory physiotherapy (breathing exercises) plays an important role in reducing and preventing respiratory complications in COVID-19 patients treated at ICU. Early mobilization and chest wall oscillation are beneficial in COVID-19 patients. We note that we are the first to conduct an evidence-based study of physiotherapy in intensive care with COVID-19 patients. We hope that our pilot clinical trial gives opportunity to future researches.

Modern biophysical view of electromagnetic processes of the phenomenon of life of living biological systems as a promising basis for the development of complex medicine: the role of water

Nevoit, Ganna — 2022-12-27T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 5, Issue 2, 2022, p. 45-57.
Ganna Nevoit, Inga Arune Bumblyte, Maksim Potyazhenko, Ozar Minser
The results of a theoretical study of the role of water in electromagnetic generation and in the process of realizing the phenomenon of life are presented in the article. This article is a continuation of the theoretical study of the team of authors, which was published in the Journal of Complexity in Health Sciences, Vol. 5, Issue 1, 2022, p. 22-34. The aim of the theoretical study was to generalize the available scientific physical and biological knowledge of modern science about the role of water in the electromagnetic processes of the phenomenon of life at the cellular level in order to deepen the fundamental knowledge of Complex Medicine. This study is a fragment of research work on “Development of algorithms and technologies for implementing a Healthy Lifestyle in patients with Noncommunicable Diseases based on the study of functional status” (state registration number 0121U108237: UDC 613 616-056-06: 616.1/9-03). General scientific methods and theoretical methods were used in this theoretical study. The main conclusions of the theoretical study were made as follows: 1) Тhe “30/11 helix” is the main most typical fragmentary element of water self-organization into fractal structures and it forms energy-intensive fractal crystalline filamentous water structures in living biological systems, supported by energy constantly coming from biopolymers, and forming large constantly growing hierarchical structures that unite all the water of a living organism in a dynamic balance of opposite processes of destruction and growth of its energy-intensive crystalline structures; 2) Water has a key role in the process of transmission and perception of the coherent energy of a soliton through self-organizing fractal energy-intensive paramagnetic crystalline structures in living biological systems; 3) The phenomenon of biological life at the micro level is characterized by the presence of a state of water binding/organization into energy-intensive crystalline structures due to the constant supply of coherent energy from biopolymers and stops when this energy flow disappears, which corresponds to the onset of the phenomenon of biological death and is manifested by the degradation of energy-intensive fractal crystalline self-organization of water to an unbound water state. solution devoid of so-called biological anomalies.

Modern biophysical view of electromagnetic processes of the phenomenon of life of living biological systems as a promising basis for the development of complex medicine: the role of biophotons

Nevoit, Ganna — 2023-06-25T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 6, Issue 1, 2023, p. 1-15.
Ganna Nevoit, Inga Arune Bumblyte, Maksim Potyazhenko, Ozar Minser, Alfonsas Vainoras
The results of a theoretical study of the role of biophotons in electromagnetic process of realizing the phenomenon of life are presented in the article. This article is a continuation of the theoretical study of the team of authors, which was published in the Journal of Complexity in Health Sciences, Vol. 5, Issue 1, 2022, p. 22-34 and Vol. 5, Issue 2, 2022, p. 45-57. The aim of the theoretical study was to generalize the available scientific physical and biological knowledge of modern science about the role of biophotons in the electromagnetic processes of the phenomenon of life at the cellular level in order to deepen the fundamental knowledge of Complex Medicine. This study is a fragment of research work on “Development of algorithms and technologies for implementing a Healthy Lifestyle in patients with Noncommunicable Diseases based on the study of functional status” (state registration number 0121U108237: UDC 613 616-056-06: 616.1/9-03). General scientific methods and theoretical methods were used in this theoretical study. Based on the results of this fragment of the theoretical study, twelve conclusions were formulated. The formulated conclusions conceptualize such basic questions as: all living cells at the nanoscale consist of electromagnetic fields and generate electromagnetic fields, cell signaling and all cellular processes are due to electromagnetic interactions, ultra-weak photon emission is a universal optical phenomenon for all cells and plays an important role in communication and in cell life throughout the body.

Application of machine learning techniques for obesity prediction: a comparative study

Dirik, Mahmut — 2023-10-06T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 6, Issue 2, 2023, p. 16-34.
Mahmut Dirik
Obesity, characterized by excess adipose tissue, is becoming a major public health problem. This condition, caused primarily by unbalanced energy intake (overconsumption) and exacerbated by modern lifestyles such as physical inactivity and suboptimal dietary habits, is the harbinger of a variety of health disorders such as diabetes, cardiovascular disease, and certain cancers. Therefore, there is an urgent need to accurately diagnose and assess the extent of obesity in order to formulate and apply appropriate preventive measures and therapeutic interventions. However, the heterogeneous results of existing diagnostic techniques have triggered a fierce debate on the optimal approach to identifying and assessing obesity, thus complicating the search for a standard diagnostic and treatment method. This research primarily aims to use machine learning techniques to build a robust predictive model for identifying overweight or obese individuals. The proposed model, derived from a person's physical characteristics and dietary habits, was evaluated using a number of machine learning algorithms, including Multilayer Perceptron (MLP), Support Vector Machine (SVM), Fuzzy K-Nearest Neighbors (FuzzyNN), Fuzzy Unordered Rule Induction Algorithm (FURIA), Rough Sets (RS), Random Tree (RT), Random Forest (RF), Naive Bayes (NB), Logistic Regression (LR), and Decision Table (DT). Subsequently, the developed models were evaluated using a number of evaluation measures such as correlation coefficient, accuracy, kappa statistic, mean absolute error, and mean square error. The hyperparameters of the model were properly calibrated to improve accuracy. The study revealed that the random forest model (RF) had the highest accuracy of 95.78 %, closely followed by the logistic regression model (LR) with 95.22 %. Other algorithms also produced satisfactory accuracy results but could not compete with the RF and LR models. This study suggests that the pragmatic application of the model could help physicians identify overweight or obese individuals and thus accelerate the early detection, prevention, and treatment of obesity-related diseases.

Application of machine learning algorithms in drug screening

Jin, Ke — 2023-11-04T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 6, Issue 2, 2023, p. 35-48.
Ke Jin, Cunqing Rong, Jincai Chang
At present, in the medical field, drug screening is usually performed using in vivo drug experiments. However, it is very time-consuming and laborious to conduct in vivo experiments on a large number of drugs to be screened one by one. This paper attempts to propose using machine learning algorithms to perform preliminary screening of a large number of compounds to be screened and their molecular structures to reduce the workload of in vivo experiments. Among them, it is internationally recognized that there is an important association between breast cancer progression and the alpha subtype of the estrogen receptor. Anti-breast cancer drug candidates with excellent efficacy need to contain compounds that can better antagonize ERα activity. In this paper, the research object is narrowed down from compounds to the molecular structure of the compounds, and then the random forest regression algorithm is used to develop the molecular structure-ERα activity prediction model. Molecular structures with significant effects on biological activity were screened from molecular structure descriptors in numerous compounds. Four different kernel functions were used to conduct comparative experiments, and finally a support vector regression algorithm based on radial basis kernel function was established, which realized the quantitative prediction of compounds on biological activity of ERα, and could find potential compounds beneficial to breast cancer treatment. This is a novel, computer-based method for preliminary drug screening, which can help medical researchers effectively narrow the scope of experiments and achieve more accurate optimization of drugs.

Modern biophysical view of electromagnetic processes of the phenomenon of life of living biological systems as a promising basis for the development of complex medicine: towards the concept of Bioelectronic Medicine

Nevoit, Ganna — 2023-12-28T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 6, Issue 2, 2023, p. 49-66.
Ganna Nevoit, Olena Filiunova, Maksim Potyazhenko, Ozar Minser, Inga Arune Bumblyte, Alfonsas Vainoras
The publication of the results of a theoretical study on the conceptualization of Bioelectronic Medicine continues a series of articles on the role of electromagnetic processes in the implementation of the phenomenon of life. The authors, based on modern biophysical fundamental knowledge about the structure and functioning of the human body at the micro level of its structure (nanolevel and deeper) and the concepts of the Magnetoelectrochemical theory of metabolism, developed the main ideological concepts of the scientific direction “Bioelectronic Medicine” as a component for the further development of complex medicine. General scientific methods and theoretical methods were used in this theoretical study. The result of this theoretical research was the extrapolation of modern biophysical fundamental data on the structure of the microcosm of matter to medical knowledge about humans. It is proposed to call the resulting scientific direction the term “Bioelectronic medicine”. A conceptualization of the obtained fundamental ideas was made, three basic concepts and seven main aspects of “Bioelectronic Medicine” were formulated.

Natural resources can help reducing cardiovascular risk: randomized controlled study

Rapolienė, Lolita — 2024-04-29T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 7, Issue 1, 2024, p. 19-31.
Lolita Rapolienė, Giedrė Taletavičienė, Arvydas Martinkėnas
Cardiovascular diseases are the leading cause of death globally accounting for 32 % of all global deaths. Addressing modifiable risk factors, including hypertension and stress, remains paramount in the prevention of CVD. This study aimed to assess the impact of the balneotherapy on blood pressure, heart rate, electrocardiogram parameters, utilization of antihypertensive medications, and stress levels. Methodology. Multicenter randomized controlled single-blind parallel group trial was made in 6 Lithuania resort centers. 373 participants with the stress level > 3 (10, VAS) randomly divided into 6 groups in two clusters for receiving a 6- or 11-day complex treatment using natural resources – mineral waters, peloids, salt, nature therapy; follow-up period was 6 months. The BP, HR, ECG, stress level and other parameters were analyzed in 131 participants who passed a full course of investigation. Results. The significant reduction of systolic blood pressure after treatment (7.8 mmHg) and during 6 months (7.3 mmHg) together with diastolic 5.5 after 6 month and heart rate (4 b/min) was achieved in 11-day ambulatory balneotherapy group. Increase in the activity of the parasympathetic nervous system was observed, which is reflected by an increase in the duration of the ECG indicators. The stress level decreased by up to 43%, and stress management improved by up to 41% following inpatient treatment. Conclusion. Therapy using natural resources could stand for additional cardiovascular disease prevention and management method in integrative therapy.

Interconnections between local Schumann resonances and episodes of kidney disease

Nevoit, Ganna — 2024-05-23T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 7, Issue 1, 2024, p. 1-18.
Ganna Nevoit, Asta Stankuviene, Gediminas Jaruševičius, Rollin McCraty, Mantas Landauskas, Maksim Potyazhenko, Inga Arune Bumblyte, Alfonsas Vainoras
The aim of the study was to evaluate the interconnections between local Schumann resonances of the Earth’s magnetic field and episodes of kidney disease. Materials and Methods: Study participants included 716 males and 624 females who had episodes of kidney disease during the period of 1 January 2021 to 31 December 2021 and attended the Department of Nephrology at the Hospital of Lithuanian University of Health Sciences, Kauno klinikos. Time varying magnetic field data was collected at the magnetometer site located in Lithuania. Results and Conclusions: The study results support the hypothesis that the Earth’s magnetic field has a relationship between the number of nephrology patient hospitalizations per week and the average weekly local Schumann resonances strength in different frequency ranges. Working hypotheses are proposed for the mechanisms of the influence of the Earth’s electromagnetic field on kidney function: а) quantum mechanical features of the atomic composition of renal tissue molecules determine a kidney-specific reaction; b) cyclotron resonance mechanism; c) resonant response of cells of morphological structures of kidney tissue to external bioactive frequencies in the range of 6-8 Hz; d) mechanism of indirect influence of blood as a magnetically saturated medium.

Hand-arm vibration analysis of Caeski: a communication device for deafblind persons

R. Luz, Taciana — 2024-09-08T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 7, Issue 2, 2024, p. 34-44.
Taciana R. Luz, Rudolf Huebner, Maria Lúcia M. Duarte, Herbert C. Nick
Assistive technologies can improve greater participation in society and sociocultural experiences. A communication device for deafblind persons, called Caeski, is an assistive technology that allows independent communication between two deafblind persons or between deafblind and non-deafblind persons using vibrating keys. The aim of this study is to analyze the effects of hand-arm vibrations (HAV) emitted by Caeski to check if this will be harmful to users. The vibrations emitted by the Caeski’s keys were analyzed from data provided by a triaxial accelerometer, positioned over the fingers of a sample of seven deafblind individuals. The obtained data are within acceptable limits set by International Health and Safety standards – ISO 8041, ISO 5349-1 and European Directive 2002/44/EC – on the physical risk of vibration. Safety is part of the product development process. It was possible to demonstrate that the proposed technology is not harmful to users and can be used safely.

Exploring additive manufacturing in assistive technologies to transform the educational experience: empowering inclusion

Domingos Dias, Wellingtânia — 2024-09-08T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 7, Issue 2, 2024, p. 81-94.
Wellingtânia Domingos Dias, Jefferson Henrique Soares, Lara Corrêa Guimarães, Natalia Espinosa Martínez, Taciana Ramos Luz, Yaçana Maria da Costa Soares Sousa Lima, Rudolf Huebner
This study explores additive manufacturing's potential in creating tailored assistive technologies, fostering inclusion in education. To design ergonomic solutions for diverse user needs, promoting inclusion and autonomy. A sequential approach involves assessment, 3D modeling, additive manufacturing, and aligning with the Inclusion Support and Accessibility Promotion Program (PIPA). Various assistive technologies were developed, addressing specific needs. The “Ergonomic Pen and Pencil Reamer” improves grip accuracy, and the “Folding Handle for Folding Cup” offers an ergonomic solution. The “Guideline Ruler” supports music education, with accessories like the “Template for Clefs and Musical Notes” and “Thimble with Support Base for Musical Instrument Strings” enhancing versatility. The “Ring with Front Support” aids art education, and the “Support for Scissors” promotes independence. These innovations contribute to inclusion and autonomy. The research underscores the importance of additive manufacturing in crafting personalized solutions, propelling inclusion in education and daily activities. Identified challenges, including material selection and adaptation to diverse needs, signal areas for future research. Continuous collaboration with end-users and professionals remains crucial for enhancing usability and effectiveness, reinforcing the commitment to promoting inclusion and autonomy.

Exploring the impacts of daytime sleepiness on gait, physical balance, and the occurrence of orofacial trauma: a narrative review

Domingos Dias, Wellingtânia — 2024-09-08T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 7, Issue 2, 2024, p. 95-102.
Wellingtânia Domingos Dias, Natalia Espinosa Martínez, Rudolf Huebner, Junia Maria Serra Negra
Daytime sleepiness (DS) often accompanies obstructive sleep apnea (OSA), exacerbating its effects. DS can impair cognitive function, attention, reaction time, and motor coordination, increasing the risk of accidents. This study aimed to explore the relationship between DS, changes in gait and balance, and the occurrence of orofacial fractures. A narrative review was conducted using PubMed, Scopus, and Web of Science publications. The analysis revealed the impact of DS and OSA on gait and balance control in older individuals, emphasizing the need for interventions to address these issues and identify associated pathologies. Continuous Positive Airway Pressure (CPAP) therapy was recognized as a potential treatment, although further research is needed to understand DS triggers and treatment options in older populations. The study underscores the importance of analyzing interactions between the central nervous system, medications, balance, and mobility to prevent falls and related injuries. While the literature highlights the vulnerability of elderly individuals and those with OSA to falls, no established link between DS, gait, balance, and orofacial trauma necessitating medical and dental intervention was found. Thus, further research is warranted to address this gap and promote better understanding and management of these conditions.

Why should a bioengineering lab have engineers and health professionals?

Santiago Jr, Orlando — 2024-09-08T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 7, Issue 2, 2024, p. 45-57.
Orlando Santiago Jr, Thiago H. R. da Cunha, Rodrigo G. Lacerda, Elizabeth Akemi Fujito, Marcus Vinicius L. Ferreira, Rudolf Huebner, Claudio L. P. Silva
Through the description of the methodology of the development of a bite force measurement device it will be shown how interdisciplinary work of Engineers and Health Professionals bring enhance of life quality to general population. Bite force measurement is a reliable exam to check stomatognathic system (SS) conditions. In order to provide a reliable, low cost and do-it-yourself gnathodynamometer a Dentist joined Bioengineering Laboratory (LabBio) at UFMG. The development of a 3D printed resin structure was made using CAD/CAM and tested by means of FEM. A Carbon Nano Tube (CNT) extensometer developed at CTNANO at UFMG to capture the structure deformation were fixed in two geometries that showed good results in FEM simulation and will be tested in an EMIC universal mechanical testing machine (DL1000) equipped with a 1 kN load cell. The electrical response of the extensometers was monitored using a Keithley 2000 digital multimeter (Tektronix), connected to a computer and remotely controlled by a LabView application (View Point Systems), a data storage protocol in a SD card and in the clouds using IoT and an data acquisition system will be tested. In bench tests both geometries showed good results with deformation capturable from 40 N. Data was codified using an Arduino Nano and a program was developed for data acquisition and storage. The interdisciplinary work generates prototypes with promising results in bench tests. The fruit of the team work may generate a toll that improves life quality of population by allowing more people to be tested and lowering health costs.

Evaluation and design of a bite force measuring load cell

Santos Rodrigues, Pedro Ivo — 2024-09-08T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 7, Issue 2, 2024, p. 76-80.
Pedro Ivo Santos Rodrigues, Orlando Santiago Júnior, Rudolf Huebner
The measurement of bite force can be essential for assessing oral health and the functioning of the stomatognathic system. However, its use in dental offices is limited due to operational complexities and costs. This study focused on evaluating the mechanical strength of the user-friendly and low manufacturing cost load cell under development within LABBIO – Bioengineering Laboratory at UFMG, the gnathodynamometer, tailored for children. 3D modeling in SolidWorks and Finite Element Method (FEM) structural analysis were employed to ensure its ability to withstand the desired 1000 N load. Initially, the device did not meet the desired load, resulting in iterations to modify its geometry. After iterations including the replacement of the initial material with a more suitable alternative, removal of edges, and other adjustments, a final prototype meeting mechanical strength and functionality requirements was developed.

Low-level laser therapy parameters in the treatment of Orofacial pain in temporomandibular disorder

De Abreu Chaves, Maria Emília — 2024-09-08T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 7, Issue 2, 2024, p. 58-65.
Maria Emília De Abreu Chaves, Mônica Goulart Fonseca, Aline Beatriz Ferreira
Temporomandibular disorder (TMD) comprises a group of dysfunctions of the masticatory system involving joint, myofascial, and even sensory alterations. The main symptom of TMD is orofacial pain, which has a negative impact on the quality of life of TMD sufferers, affecting their productivity at work and school, the quality of their sleep, their appetite, and their satisfaction with life. An alternative for the treatment of TMD is the low-level laser therapy (LLLT), which stimulates cellular functions and promotes therapeutic effects. However, there is no consensus in the literature. Objective: This review aimed to elucidate the parameters of low-level laser therapy in the treatment of orofacial pain in patients with temporomandibular disorder. Methods: A search was carried out for scientific articles published between 2013 and 2023 in the MEDLINE, PEDro, LILACS and SciELO databases. Results: A total of 21 studies were previously selected and after the eligibility criteria, 10 studies were included. Can be suggest a protocol for treating patients with temporomandibular disorder by low-level laser therapy with the following parameters: infrared wavelength, energy density less than 10 J/cm2, output power from 100 to 250 mW and at least 8 sessions of treatment. Conclusion: The low-level laser therapy improves orofacial pain in patients with temporomandibular disorder.

Dynamic pupillometry system

Bim, Camila — 2024-09-09T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 7, Issue 2, 2024, p. 109-118.
Camila Bim, Jean Andrade Canestri, Ricardo Guimarães, Marcos Pinotti
The phenomena of miosis (constriction) and mydriasis (dilation) of the pupil are exhibited in response to varying levels of light intensity cast upon the eye. In general, the size and responsiveness of the human pupil are under the regulatory purview of the nervous system. Consequently, the study of the pupil offers a means to discern potential abnormalities in the human organism, as it permits an assessment of the nervous system’s behavior. However, the comprehension of pupillary dynamics remains incomplete in certain facets, and methodologies for enhancing diagnostic precision continue to evolve, primarily contingent upon current technological equipment advancements. Thus, the imperative lies in the advancement of technologies that meet these research needs, as the scrutiny of pupillary responses holds the capability to detect anomalies within the human body. Hence, the objective of this endeavor is to conduct preliminary trials of a dynamic pupillometry system, designed to both stimulate and capture images of human pupils, facilitating an investigation into their behavioral patterns. The findings elucidate various pupillary parameters and reveal significant alterations in pupillary conduct, thereby contributing to the advancement of research and technologies within the realm of pupillometry. Thus, this study undertakes an innovative exploration into pupillometry, particularly regarding stimuli of varying wavelengths, thereby providing improvements on the diagnostic, prognostic and preventive capacity with heightened reliability, given the pupil’s size and its reactions cannot be manipulated or falsified since they are involuntary.

Photogrammetry protocol in babies with congenital torticollis: part 1 – inter-arch intraoral assessment

Bittar, Karina Correia Bonalumi — 2024-09-09T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 7, Issue 2, 2024, p. 125-133.
Karina Correia Bonalumi Bittar
Torticollis is defined as an imbalance of the sternocleidomastoid muscle (SCM), with less extension of the neck, resulting in a preference to turn the head more from one side to the other. The characteristics frequently found are: ear contralateral to the torticollis displaced forward, facial asymmetry, and contralateral occipital flattening, as well as a smaller ipsilateral eye, causing misalignment of the eyes. This condition can also cause mandibular inclination (MI), in the frontal plane, with a difference in opening between the maxilla and mandible from one side or the other. The diagnosis and treatment of torticollis are routinely carried out by the physiotherapist and the diagnosis of this mandibular inclination is traditionally through visual examination. This assessment of mandibular inclination, carried out by the dentist, in an objective manner, can contribute to the diagnosis and also to the monitoring of proposed treatments that should reduce mandibular asymmetries. The objective of this study was to create a protocol for objective measurement of the distance between the maxilla and mandible, on the right and left sides, using photogrammetry, to detect whether mandibular inclination can be observed by the shorter inter-arch distance on the side corresponding to the torticollis. Case reports of two babies (1 baby aged 9 months and another aged 1 year and 1 month), diagnosed with congenital torticollis. Photogrammetry was carried out: the babies were positioned on a dental stretcher and photographed in maximum opening, intermediate, and closing positions. Using the photos and the IMAGE J program, measurements between the maxilla and mandible were taken (see photogrammetry description). Results: The measurement protocol used in both babies confirmed the greater mandibular inclination by approaching the hemi-arch corresponding to the side of the torticollis, compared to the opposite side. Objective measurement of mandibular inclination can be part of the timely diagnosis for congenital torticollis. Studies with an adequate sample size and methodology are necessary to confirm this diagnostic tool.

Open-source hand prosthesis: evaluation of mechanical feasibility and additive manufacturing potential

Romero, Rodrigo Cézar Da Silveira — 2024-09-25T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 7, Issue 2, 2024, p. 103-108.
Rodrigo Cézar Da Silveira Romero, Kliftom Amorim Costa, Claysson Bruno Santos Vimieiro
This study delves into the risks associated with 3D-printed hand prostheses lacking mechanical feasibility studies. Such unvalidated prostheses may exhibit various issues like durability shortcomings, anatomical incompatibility, functional safety concerns, manufacturing quality deficiencies, and health risks due to inappropriate materials. These issues can lead to damage or premature failure during use, discomfort, skin irritation, injuries, inability to withstand functional loads, and health hazards from toxic or allergenic substances. Therefore, ensuring the safety, quality, and effectiveness of these prostheses is crucial. The study focuses on a mechanical feasibility study conducted through Finite Element Analysis (FEA) simulations on an open-source hand prosthesis model. It evaluates mechanical properties, stress concentration areas, and displacement on the prosthesis surface. The methodology comprises three key steps: acquiring the virtual model, conducting computational simulations, and selecting the 3D printing material. The simulations assess the prosthesis’s ability to withstand compressive forces and identify stress concentration areas. Results from the study indicate that using PETG as the constituent material demonstrates mechanical viability and satisfactory performance under static force conditions. This finding underscores the importance of rigorous testing and adherence to standards in developing 3D-printed hand prostheses. Such studies contribute significantly to enhancing these devices’ safety and effectiveness, facilitating their broader adoption in healthcare settings. In summary, this study highlights the critical need for mechanical feasibility studies in the development of 3D-printed hand prostheses. It emphasizes the significance of following strict standards and regulations to ensure these devices’ safety, quality, and functionality. By doing so, it paves the way for the widespread use of these prostheses in healthcare, benefiting users and advancing the field of prosthetic technology.

Advances of 3D printing in oral oncology: personalized technologies for patients – a narrative review

Castro-Braga, Mirian — 2024-09-25T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 7, Issue 2, 2024, p. 66-75.
Mirian Castro-Braga, Wellingtânia Domingos Dias, Raquel Fabiane Nogueira, Lucas Guimarães Abreu, Rudolf Huebner, Junia Maria Serra-Negra
This study presents a narrative review of the literature that focuses on the substantial relevance and practical application of additive manufacturing and 3D printing in the context of oncology patients in the dental field. To address innovative technologies for diagnosis and treatment, this review underscores the progressive role of 3D printing in the creation of customized models for rehabilitation, surgical planning, prosthetics, examinations, and even tissue engineering. We analyzed five articles focused on the following categories: applications, benefits, and challenges associated with additive manufacturing; 3D printing; head and neck cancer; as well as assistive technology in the context of improving the effectiveness of treatments for people with this type of neoplasm. Oropharyngeal squamous cell carcinoma stood out as the most cited neoplasm for the use of 3D printing. 3D printing has played a significant role in transforming oral cancer treatment by providing customized solutions and enhancing outcomes: custom implants and prosthetics, patient-specific radiotherapy accessories, dose modulation devices, and improved preoperative planning. Additionally, 3D printing enables the production of complex medical devices in a single process, reducing steps and potentially costs. This also opens doors to creating more affordable solutions and extends the reach of personalized treatment to a greater number of patients. Continuous advancements in research and development of additive manufacturing and 3D printing technologies demonstrate significant potential for optimizing treatments and improving outcomes for patients with head and neck cancer.

Use of hyperboloid as an adjunct in functional jaw orthopedics – case report

Augusto Novo Borghi, Fabiana — 2024-09-25T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 7, Issue 2, 2024, p. 134-140.
Fabiana Augusto Novo Borghi
Anterior open bite can be defined as a malocclusion with a negative vertical discrepancy between the incisal edges of the upper and lower anterior teeth, which do not have occlusal contacts with the antagonists and sometimes extends to the canines and, less frequently, to the premolars is one of the malocclusions with the greatest aesthetic and/or functional impairment. Anterior open bite can have several etiologies: finger sucking and/or pacifier, oral breathing, onychophagia, lip interposition, atypical swallowing, tongue interposition when uttering phonemes and anterior posture of the tongue at rest. Orofacial myofunctional disorders are present in cases of anterior open bite, generally associated with etiologies and adapt to this altered morphological condition. Regarding the anterior opening amplitude, the anterior open bite is classified as: minimum up to 1 mm, moderate between 1 and 5 mm and severe +5 mm [1]. Open bite can be classified into: maxillary, mandibular and hybrid open bite [2]. Myofunctional therapy is considered a treatment method that can increase muscle strength, cause changes in functional patterns and thus prevent deviations in craniofacial development, as it promotes new posture of structures at rest and during the performance of the functions of the stomatognathic system [3]. The hyperboloid is an instrument for increasing muscle tone and when used in chewing, it is efficient in inducing growth and remodeling. The hyperboloid fills a gap in the modern diet, with the consistency of hard, raw and dry foods [4]. Exercises with a size M hyperboloid with wire were prescribed as an initial approach. After 2 months of treatment, there was an improvement in the interincisor distance. The exercise was maintained for another 5 months. He stopped attending appointments for 2 years and 2 months. Upon his return, the results of the functional examination of swallowing, chewing, protrusion and laterality were observed, and we opted for the installation of the SN3. the hyperboloid, in this case, showed its efficiency in balancing the stomatognathic system.

Welcoming pregnant women as a strategy for adherence to dental prenatal care and health promotion in early childhood

Mendes Orsi, Renata — 2024-10-06T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 7, Issue 2, 2024, p. 119-124.
Renata Mendes Orsi, Ligia Ferreira Gomes
This research deals with implementing Dental Prenatal Care as a public policy in the Brazilian Unified Health System (SUS) to care for pregnant women and their future babies. The legal framework that assures pregnant women's rights of priority in accessing services is usually not enough to guarantee the health promotion coverage goals for this population group, who frequently have low adherence to dental care. Brazilian Unified Healthcare System (SUS) recommends monitoring pregnant women through eight mensal consultations during healthy pregnancy. Oral health is usually not monitored to the same extent, and many pregnant women still go through pregnancy without any dental consultation. This study was proposed to improve dental prenatal care and program adherence by mothers and children in the Basic Healthcare Unit Amaro José de Souza, in the municipality of Barueri, through the increased participation of the dental surgeon in the pregnant women welcoming team. A cross-sectional cohort study was designed to identify and meet the demands of low-risk pregnant women. For six months, all the women attending prenatal care at BHU Amaro José de Souza in Barueri were invited to participate and receive personal guidance from the multi-professional team. Information on dental health was investigated through questions targeting previous knowledge about the recommended moments for the first dental appointment of a child, the importance of exclusive nasal respiration, the identification of craniofacial asymmetries at birth, and general baby care. Attitudes and self-care were also investigated, including prenatal program adherence. Answers were collected in a Google Form platform and analyzed to characterize the group's literacy about prenatal care and breastfeeding and identify information needs about dental health care during pregnancy. At the same time, a welcoming expanded listening, educational, and preventive health action was developed: conversation and sharing experience groups were promoted monthly for pregnant women, breastfeeding mothers, and their families. 90 pregnant women out of the 104 attending the BHU in the six months of the research were invited, and 83 agreed to participate. All the participants declared at least one previous appointment with the healthcare team, 92.8 % of them, with a gynecologist. The nursing team was involved in 53.0 % of the appointments, but only 6.0 % were reported to have been conducted exclusively by a nurse. A dental surgeon appointment was mentioned by 30.1 % of the research participants. The dental health literacy investigation revealed that 57.8 % believed they should only take their babies to a dental appointment after teething, and 27.7 % were aware of the child's craniofacial asymmetries at birth. Only 28.9 % had previous knowledge about the importance of exclusive nasal respiration. Despite only 34.9 % having their first pregnancy, 78.3 % declared they would appreciate receiving information about pregnancy. After the guidance, 72.0 % of the pregnant women had undergone dental prenatal care. Workshops for pregnant women and breastfeeding mothers provided a convenient welcoming space, to listen and provide guidance to pregnant women and their families, in addition to demystifying the fear of dental care during pregnancy and breastfeeding. The intervention to guide pregnant women to perceive the BHU as an educational and health promotion space, not just a curative intervention, effectively increased adherence to dental prenatal care. The contact with the Specialist in Functional Jaw Orthopedics in this first phase of life facilitated dental health education and access to more complex cases. The prenatal program adherence, the pregnant woman’s self-care, and the care of the baby were favored by the welcoming, expanded listening, and personalized service.

Individualized recommending exercises and improving DINA algorithm by CLP-parameter adjustments

Lyu, Yuhan — 2024-12-26T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 8, Issue 1, 2025, p. 1-11.
Yuhan Lyu, Wei Liu, Jianxing Yu, Jian Yin
The traditional mode of education has been integrated with the technologies of internet to give rise to smart and or intelligent assistant education. A recommender “recommending items to customers” has been applied with great success in many commercial platforms, such as Amazon, Google, JD.com, and Tiktok, but there still has been no such an assisted learning system that effectively “recommending exercises (as the items) to learners (as the customers)”. This paper addresses the problems and challenges in applying recommender technology to the design of an intelligence-assisted learning system for individualized exercises recommendation. After providing an overview with some analysis on state-of-the-art researches, a model is proposed to improve DINA algorithm by four adjustments with changeable parameters of cognitive level perception (CLP), together with three primary steps of implementation in practice. It aims to improve recommendation accuracy of the mostly-concerned DINA algorithm based on widely-concerned cognitive diagnosis method (CDM). The proposed algorithm would have better performances on individualized exercises recommendation due to better CLP-capability. Another part of this study will provide further verification of the performances.

Editor’s Letter. Special issue on bioengineering innovations at Bioengineering Laboratory of the Federal University of Minas Gerais

Santiago Jr., Orlando — 2024-12-31T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 7, Issue 2, 2024, p. 32-33.
Orlando Santiago Jr., Rudolf Huebner

Vega test method and diagnosis of non-communicable Diseases: problems, biophysical diagnostic mechanisms and prospects

Nevoit, Ganna — 2025-03-01T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 8, Issue 1, 2025, p. 12-28.
Ganna Nevoit, Olena Filyunova, Svetlana Danylchenko, Maksim Potyazhenko, Ozar Mintser, Inga Arune Bumblyte, Alfonsas Vainoras
This theoretical research is part of the educational and scientific project “Bioelectronic medicine or look at medicine differently” of research work of the Department of Internal Medicine and Emergency Medicine of Poltava State Medical University (23, Shevchenko St., 36011, Poltava, Ukraine) on “Development of algorithms and technologies for implementing a Healthy Lifestyle in patients with Non-Communicable Diseases (NCDs) based on the study of functional status” (state registration number 0121U108237: UDC 613 616-056-06: 616.1 / 9-03). The aim of this theoretical research was to create a systemic medical analysis of the nutrition of the scientific evidence of the Vega Test Method in the complex clinical treatment of patients with Non-Сommunicable Diseases, to determine the current state of health problems and prospects for using the method from the perspective of Complex Medicine. Conclusions: Vega Test Method is a promising modern science-intensive computerized instrumental technique that should be introduced into Clinical Medicine for the examination of patients with NCDs. Existing problems of introducing the Vega Test Method into Clinical Medicine are solved thanks to the progress of fundamental science and Quantum Physics, which leads to a paradigm shift in views on the functioning of the human body. The Vega Test Method has a modern scientific biophysical justification of validity mechanisms based on knowledge of the Magneto-Electrochemical Theory of Metabolism and Life, the Theory of the Electromagnetic Field, and the Concept of Biophoton Signaling. The use of the Vega Test Method in Clinical Medicine for the examination of patients with NCDs is important for the development of Complex Medicine.

Magnetoelectrochemical theory of metabolism and life is a new trend in complexity in health sciences

Nevoit, Ganna — 2025-09-03T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 8, Issue 2, 2025, p. 42-53.
Ganna Nevoit, Kristina Poderiene, Svetlana Danylchenko, Oksana Kitura, Nadiia Liulka, Igor Golovchenko, Maksim Potyazhenko, Ozar Mintser, Gediminas Jarusevicius, Alfonsas Vainoras
In 2018, research was initiated to investigate the role of electromagnetic processes in human metabolism. This theoretical research is part of the research work of the Department of Internal Medicine and Emergency Medicine of Poltava State Medical University (23, Shevchenko St., 36011, Poltava, Ukraine) on “Development of algorithms and technologies for implementing a Healthy Lifestyle in patients with Non-Communicable Diseases (NCDs) based on the study of functional status” (state registration number 0121U108237: UDC 613 616-056-06: 616.1/9-03). The results of this work were embodied in the conceptualization of the Magnetoelectrochemical Theory of Metabolism and Life. The purpose of this article is to present to the academic community brief information about the results of the research work carried out in this direction for the further development of these scientific ideas and their integration into the scientific paradigm. Conclusions: 1) Magnetoelectrochemical Theory of Metabolism and Life is a new trend in Complexity in Health Sciences. 2) The biophysical direction of development of modern medicine opens up new ways to solve the problems of diseases of internal organs. 3) Knowledge of the fundamental aspects of electromagnetic communication of cells of the human body is a new basis for deepening the fundamental knowledge of the pathogenesis of diseases of internal organs, and this is a new promising direction for further research. 4) Bioelectronic Medicine, as a new component of medical science, is based on and directs therapeutic influence on the quantum levels of the structure and functioning of the human body. 5) The initiative educational and scientific project “Bioelectronic Medicine or Look at Medicine Differently” is a practical attempt in the conditions of the scientific present to find a way to change the scientific paradigm and popularize the latest knowledge among the academic community of the biomedical direction. 6) The practical application of this knowledge opens up new avenues for the further development of Magnetobiology, Internal Medicine, Microbiology, and Traditional Medicine. It can ensure progress in the treatment of diseases of internal organs, whether infectious or non-infectious in origin.

Exercita Rim – physical exercise protocol with blood flow restriction for people with chronic kidney disease on conservative treatment

Pereira Caetano, Antonio Filipe — 2025-12-30T00:00:00Z

Journal of Complexity in Health Sciences, Vol. 8, Issue 2, 2025, p. 29-41.
Antonio Filipe Pereira Caetano, Janyeliton Alencar De Oliveira, Camila Fernandes Pontes Dos Santos, Amaro Wellington Da Silva, Michelle Jacintha Cavalcante Oliveira, Maria Do Socorro Cirilo Sousa
Physical exercise promotes benefits for people with chronic kidney disease, but little has been investigated on the effects of strength training using the blood flow restriction method. The objective is to present the intervention protocol with strength physical exercise associated with the RFS method for people with stage 3 CKD and to report the benefits in the hemodynamic scope and personal satisfaction after 4 weeks of exposure to physical exercise. The study is an intervention protocol proposed to be developed over 12 weeks, with 9 exercises, in people with CKD-3, on 3 days a week lasting 50 minutes. The participants were divided into groups with low load, with high load and group with blood flow restriction and hemodynamic variables (blood pressure and heart rate) and affective satisfaction in relation to the proposed exercise were measured. Forty people aged 58±8.9 years were recruited, of which 30 participated in the intervention. Regarding satisfaction, the high-load group presented better results (2.8 to 3.5) (p= 0.035); and for blood pressure, the blood flow restriction group showed significance in systolic pressure (p= 0.034). It is concluded that after 4 weeks of intervention with a strength training protocol aimed at blood flow restriction, there are trends of improvements in systolic blood pressure levels, and affective sensations were improved after the end of the exercise sessions.

Editor’s Letter

Berškienė, Kristina — 2026-02-22T00:00:00Z

Journal of Complexity in Health Sciences, (in Press).
Kristina Berškienė